Bone Abstracts

Background: Alzheimer’s dementia (AD) and osteoporosis (OP) are common and parallel ageing and frequently coexist in an ageing population. Low BMD appears related to increased risk of AD. Various clinical conditions have been shown to alter acetylcholine (Ach) signalling and affect bone. Ach receptor (AchR) subunits and Ach esterase (AchE) are expressed in bone. Presynaptic Botox inhibit Ach release and impair bone healing and decrease bone mineral content. Poliomyelitis ...

Background: Osteoporosis is not a homogenous disease. Riggs et al. identified two distinct types of osteoporosis, with different pathophysiology, patterns of bone loss and fracture types.Post-menopausal (PM) osteoporosis is triggered by withdrawal of the effect of oestrogen on bone, which leads to a sharp acceleration of bone turnover with an imbalance towards excessive osteoclastic activity. Senile osteoporosis in the old old (usually after the...